製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to TPM4
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Human TPM4 (N terminal).
    Database link: NM_003290

  • ポジティブ・コントロール
    • Skeletal muscle

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab93645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報
    IHC-P: 1/200 - 1/500.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
    • 組織特異性
      Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level).
    • 配列類似性
      Belongs to the tropomyosin family.
    • ドメイン
      The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
    • 細胞内局在
      Cytoplasm > cytoskeleton.
    • Information by UniProt
    • 参照データベース
    • 別名
      • epididymis secretory protein Li 108 antibody
      • HEL-S-108 antibody
      • TM30p1 antibody
      • TMP 4 antibody
      • TPM4 antibody
      • TPM4_HUMAN antibody
      • Tropomyosin 4 antibody
      • Tropomyosin alpha 4 chain antibody
      • Tropomyosin alpha-4 chain antibody
      • Tropomyosin-4 antibody
      • wu:fb06e07 antibody
      • zgc:103436 antibody
      • zgc:63909 antibody
      see all

    Anti-TPM4 antibody 画像

    • ab93645, at 1/100 dilution, showing cytoplasmic staining of TPM4 in formalin-fixed, paraffin-embedded skeletal muscle by Immunohistochemistry.

    プロトコール

    Anti-TPM4 antibody (ab93645) 使用論文

    ab93645 has not yet been referenced specifically in any publications.

    Product Wall

    Abreviews
    Abcam has not validated the combination of species/application used in this Abreview.
    Application
    Western blot
    Sample
    Human Cell lysate - whole cell (Rh30)
    Loading amount
    20 µg
    Specification
    Rh30
    Gel Running Conditions
    Non-reduced Denaturing (NuPAGE 4-12% Bis-Tris Gel)
    Blocking step
    Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: rt°C
    Username

    Abcam user community

    Verified customer

    投稿 Mar 14 2013

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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