製品の概要

  • 製品名Anti-Toxoplasma gondii antibody [TP3]
    Toxoplasma gondii 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [TP3] to Toxoplasma gondii
  • 特異性This antibody reacts with p30 membrane protein in ELISA and immunoblotting
  • アプリケーション適用あり: ELISA, ICC/IF, WBmore details
  • 免疫原

    Tachizoites lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPBS with 0.1% sodium azide, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名TP3
  • ミエローマSp2/0
  • アイソタイプIgG2a
  • 軽鎖の種類unknown
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab8313 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
WB Use at an assay dependent concentration.

ターゲット情報

  • 関連性Toxoplasma is a crescent shaped sporozoan that lives as an intracellular parasite in various tissues of many vertebrates and completes its life cycle in a single host. Its life cycle includes two phases called the intestinal (or enteroepithelial) and extraintestinal phases. The intestinal phase produces oocysts and occurs only in cats, wild as well as domesticated. The extraintestinal phase occurs in all infected animals including cats, and produces tachyzoites (actively proliferating trophozoites) and eventually, bradyzoites (slowly growing trophozoites) or zoitocysts. Infection due to Toxoplasma gondii occurs in pregnant women where a variable degree of immunosuppression may exist or in patients receiving immunosuppressive drug therapy. Toxoplasma infects tissue of the GI tract where an active infection is accompanied by fever and enlargement of the spleen. Symptoms of toxoplasmosis are generally mild but severe infection of lymph nodes may occur. Congenital toxoplasmosis, in which the maternal infection is transmitted during pregnancy, can produce blindness or mental retardation in the newborn.
  • 別名
    • T. gondii antibody

Anti-Toxoplasma gondii antibody [TP3] (ab8313) 使用論文

This product has been referenced in:
  • Zheng B  et al. The virulence-related rhoptry protein 5 (ROP5) of Toxoplasma Gondii is a novel vaccine candidate against toxoplasmosis in mice. Vaccine 31:4578-84 (2013). Read more (PubMed: 23928460) »
  • Kravets E  et al. The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii. J Biol Chem 287:27452-66 (2012). ICC/IF . Read more (PubMed: 22730319) »

See all 3 Publications for this product

Product Wall

Thank you for your enquiry. To use this antibody in IF I would recommend starting at a dilution of 1:100 or 1:200. Your customer will have to optimize based upon their results. Also, I updated our online datasheet to include the concentration of the cu...

Read More

Thank you for your enquiry. The antibody TP3 reacts only with p30 band in Western Blotting. It has been tested with purified Toxoplasma antigen and tachyzoites lysate.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"