製品の概要

  • 製品名
  • 製品の詳細
    Mouse monoclonal to TOP3B
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-863 of Human TOP3B

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度
    Protein G purified
  • ポリ/モノ
    モノクローナル
  • アイソタイプ
    IgG2b
  • 軽鎖の種類
    kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab56445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報
    WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Possesses negatively supercoiled DNA relaxing activity.
    • 組織特異性
      Isoform 1 is found in testis, heart and skeletal muscle. A 4 kb transcript which probably represents isoform 2 is found in thymus, kidney and pancreas.
    • 配列類似性
      Belongs to the prokaryotic type I/III topoisomerase family.
      Contains 1 Toprim domain.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DNA topoisomerase 3 beta 1 antibody
      • DNA topoisomerase 3-beta-1 antibody
      • DNA topoisomerase III beta 1 antibody
      • DNA topoisomerase III beta-1 antibody
      • FLJ39376 antibody
      • TOP 3B antibody
      • TOP3B antibody
      • TOP3B_HUMAN antibody
      • TOP3B1 antibody
      • Topo III beta antibody
      • Topoisomerase (DNA) III beta antibody
      • Topoisomerase DNA III beta antibody
      • Topoisomerase III beta antibody
      see all

    Anti-TOP3B antibody 画像



    • Predicted band size : 97 kDa
      TOP3B antibody (ab56445) at 1ug/lane + K-562 cell lysate at 25ug/lane.

    プロトコール

    Anti-TOP3B antibody (ab56445) 使用論文

    This product has been referenced in:
    • Yang Y  et al. Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation. Mol Cell 53:484-97 (2014). Read more (PubMed: 24507716) »
    • Stoll G  et al. Deletion of TOP3ß, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders. Nat Neurosci 16:1228-1237 (2013). Read more (PubMed: 23912948) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab56445.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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