Anti-Tomosyn 抗体 (ab101998)

製品の概要

• 製品名
  Anti-Tomosyn antibody
  Tomosyn 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to Tomosyn
• アプリケーション
  適用あり: WBmore details
• 種交差性
  交差種: Human
  交差が予測される動物種: Mouse, Rat
• 免疫原

  Recombinant protein fragment contain a sequence corresponding to a region within amino acids 3-178 of Human Tomosyn.

• ポジティブ･コントロール
  • NT2D1, IMR32, U-87 MG, MCF7 whole cell lysate

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• バッファー
  Preservative: 0.01% Thimerosal (merthiolate)
  Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Neuroscience
  • Neurotransmission
  • Secretory Vesicles
  • Regulation

  • Neuroscience
  • Neurotransmission
  • Secretory Vesicles
  • SNAPs & SNAREs

  • Neuroscience
  • Neurotransmission
  • Secretory Vesicles
  • Munc18

  • Neuroscience
  • Neurotransmission
  • Secretory Vesicles
  • Other

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • MCF7 whole cell lysate (ab3871)

アプリケーション

ターゲット情報

• 関連性
  Tomosyn plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release by inhibiting the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane, via the displacement of munc18 from syntaxin-1. There are three splice variants of tomosyn designated m-tomosyn, b-tomosyn and s-tomosyn. Although b-tomosyn is ubiquitously expressed, s-tomosyn and m-tomosyn are expressed primarily in brain.
• 細胞内局在
  Cell Membrane and Cytoplasmic. Note: Cytoplasmic, and associated with vesicular membranes and the plasma membrane. Detected at synapses and on synaptic vesicles
• 参照データベース
  • Entrez Gene: 134957 Human
  • Entrez Gene: 78808 Mouse
  • Entrez Gene: 81022 Rat
  • Omim: 604586 Human
  • SwissProt: Q5T5C0 Human
  • SwissProt: Q8K400 Mouse
  • SwissProt: Q9WU70 Rat
  • Unigene: 93534 Human

  • Unigene: 331751 Mouse
  • Unigene: 96029 Rat

  see all
• 別名
  • FLJ30922 antibody
  • Lethal(2) giant larvae protein homolog 3 antibody
  • LGL3 antibody

  • LLGL3 antibody
  • MGC141942 antibody
  • MGC141968 antibody
  • Nbla04300 antibody
  • STXBP5 antibody
  • Syntaxin binding protein 5 antibody
  • Tomosyn 1 antibody

  see all

プロトコール

• Western blot protocols