Rabbit polyclonal to Tomoregulin-1 precursor
Synthetic peptide conjugated to KLH derived from within residues 300 to the C-terminus of Human Tomoregulin-1 precursor.
(Peptide available as
This antibody gave a positive signal in human adult and fetal heart tissue lysates.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/250. Detects a band of approximately 45 kDa (predicted molecular weight: 41 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.
Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.
Belongs to the tomoregulin family.
Contains 1 EGF-like domain. Contains 2 Kazal-like domains.
Information by UniProt
C9orf3 TMEFF1 antibody
C9orf30 TMEFF1 antibody
Western blot - Anti-Tomoregulin-1 precursor antibody (ab80878)
All lanes :
Anti-Tomoregulin-1 precursor antibody (ab80878) at 1/250 dilution
Lane 1 :
Heart (Human) Whole Cell Lysate - fetal normal tissue
Lane 2 :
Human heart tissue lysate - total protein (
Lysates/proteins at 10 µg per lane.
Secondary All lanes :
Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size:
Observed band size:
45 kDa (
why is the actual band size different from the predicted?
Additional bands at:
37 kDa (possible isoform)
This antibody was raised against an immunogen that is predicted to cross react with both isoform 1 (41 kDa) and isoform 2 (37 kDa) of Tomoregulin-1 precursor. We believe that the band observed at 37 kDa seen in lane 1 corresponds to isoform 2.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"