The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報Peptide ELISA: antibody detection limit dilution 1/64000.
WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 53 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.
配列類似性Belongs to the TOM1 family. Contains 1 GAT domain. Contains 1 VHS domain.
翻訳後修飾Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.