Anti-Tollip 抗体 (ab37155)
Key features and details
- Rabbit polyclonal to Tollip
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-Tollip antibody
Tollip 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Tollip -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat -
免疫原
Synthetic peptide corresponding to 16 amino acids near to the C terminus of the human Tollip protein.
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ポジティブ・コントロール
- WB: Rat brain cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab37155の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 30 kDa).
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 30 kDa). |
ターゲット情報
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機能
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. -
配列類似性
Belongs to the tollip family.
Contains 1 C2 domain.
Contains 1 CUE domain. -
翻訳後修飾
Phosphorylated by IRAK1 upon stimulation by IL-1 or microbial products. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 361677 Rat
- SwissProt: A2RUW1 Rat
- Unigene: 137040 Rat
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別名
- Adapter protein antibody
- FLJ33531 antibody
- IL 1RAcPIP antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab37155 は 4 報の論文で使用されています。
- Huang L et al. Tollip promotes hepatocellular carcinoma progression via PI3K/AKT pathway. Open Med (Wars) 17:626-637 (2022). PubMed: 35434373
- Zhi H et al. Tollip Negatively Regulates Vascular Smooth Muscle Cell-Mediated Neointima Formation by Suppressing Akt-Dependent Signaling. J Am Heart Assoc 7:N/A (2018). PubMed: 29887521
- Iyer RP et al. Defining the sham environment for post-myocardial infarction studies in mice. Am J Physiol Heart Circ Physiol 311:H822-36 (2016). PubMed: 27521418
- Vartanian KB et al. LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury. J Neuroinflammation 8:140 (2011). WB . PubMed: 21999375