製品の概要

  • 製品名Anti-Tnk1 antibody [3F11H6]
    Tnk1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [3F11H6] to Tnk1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Purified truncated recombinant human Tnk1 (aa451-560)-His expressed in E.coli strain BL21 (DE3)

  • ポジティブ・コントロール
    • Truncated Tnk1-His recombinant protein.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70402 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: 1/10000.
    WB: 1/500 - 1/2000. Detects a band of approximately 17 kDa (predicted molecular weight: 73 kDa). Note: ab70402 has only been tested against a truncated recombinant protein.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
    • 組織特異性Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain.
    • 配列類似性Belongs to the protein kinase superfamily. Tyr protein kinase family.
      Contains 1 protein kinase domain.
      Contains 1 SH3 domain.
    • 翻訳後修飾Autophosphorylated on tyrosine residues.
    • 細胞内局在Cytoplasm. Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD38 negative kinase 1 antibody
      • EC 2.7.10.2 antibody
      • Kinase of embryonic stem cells antibody
      • Kos 1 antibody
      • Kos1 antibody
      • MGC46193 antibody
      • Non receptor tyrosine protein kinase TNK 1 antibody
      • Non receptor tyrosine protein kinase TNK1 antibody
      • Non-receptor tyrosine-protein kinase TNK1 antibody
      • Tnk 1 antibody
      • Tnk1 antibody
      • TNK1_HUMAN antibody
      • Tyrosine kinase non receptor 1 antibody
      see all

    Anti-Tnk1 antibody [3F11H6] 画像

    • All lanes : Anti-Tnk1 antibody [3F11H6] (ab70402) at 1/500 dilution

      Lane 1 : Molecular weight markers
      Lane 2 : Truncated Tnk1-His recombinant protein


      Predicted band size : 73 kDa
      Observed band size : 17 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 25 kDa. We are unsure as to the identity of these extra bands.

    Anti-Tnk1 antibody [3F11H6] (ab70402) 使用論文

    ab70402 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab70402.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"