製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to TNFSF9
  • アプリケーション
    適用あり: IHC-P, ELISA, WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide (Human) from an internal sequence.

  • ポジティブ・コントロール
    • HeLa cells and extracts from HUVEC cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab64912 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration. PubMed: 25409517
ELISA 1/20000.
WB 1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 27 kDa).
ICC/IF 1/500 - 1/1000.

ターゲット情報

  • 機能
    Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
  • 組織特異性
    Expressed in brain, placenta, lung, skeletal muscle and kidney.
  • 配列類似性
    Belongs to the tumor necrosis factor family.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 4 1BB L antibody
    • 4 1BB ligand antibody
    • 4 1BBL antibody
    • 4-1BB ligand antibody
    • 4-1BBL antibody
    • Cd137l antibody
    • Cd157l antibody
    • Homolog of mouse 4 1BB L antibody
    • Homolog of mouse 4 1BBL antibody
    • ILA ligand (TNF related) antibody
    • Ly63l antibody
    • Receptor 4 1BB ligand antibody
    • TNF superfamily member 9 antibody
    • TNFL9_HUMAN antibody
    • Tnfsf9 antibody
    • TNLG5A antibody
    • Tumor necrosis factor (ligand) superfamily member 9 antibody
    • Tumor necrosis factor ligand 5A antibody
    • Tumor necrosis factor ligand superfamily member 9 antibody
    • Tumor necrosis factor superfamily member 9 antibody
    see all

画像

  • ab64912, at a 1/500 dilution, staining Human TNFSF9 in HeLa cells, by Immunofluorescence, with (+) or without (-) immunising peptide.
  • All lanes : Anti-TNFSF9 antibody (ab64912) at 1/500 dilution

    Lane 1 : Extracts from HUVEC cells
    Lane 2 : Extracts from HUVEC cells with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 27 kDa
    Observed band size : 25 kDa (why is the actual band size different from the predicted?)

参考文献

This product has been referenced in:
  • Yoshimori M  et al. CD137 expression is induced by Epstein-Barr virus infection through LMP1 in T or NK cells and mediates survival promoting signals. PLoS One 9:e112564 (2014). IHC-P . Read more (PubMed: 25409517) »
  • Dumitriu IE  et al. High levels of costimulatory receptors OX40 and 4-1BB characterize CD4+CD28null T cells in patients with acute coronary syndrome. Circ Res 110:857-69 (2012). Read more (PubMed: 22282196) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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