FITC Anti-GITR 抗体 [DTA-1] (ab72404)
Key features and details
- FITC Rat monoclonal [DTA-1] to GITR
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2b
Related conjugates and formulations
製品の概要
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製品名
FITC Anti-GITR antibody [DTA-1]
GITR 一次抗体 製品一覧 -
製品の詳細
FITC Rat monoclonal [DTA-1] to GITR -
由来種
Rat -
標識
FITC. Ex: 493nm, Em: 528nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to TNFSF18/GITRL. Mouse CD25+ CD4+ T cell line.
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ポジティブ・コントロール
- Flow Cyt: Mouse splenocytes.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
バッファー
pH: 8.00
Preservative: 0.05% Sodium azide
Constituents: 0.88% Sodium chloride, 0.12% Tris, 0.05% BSA -
Concentration information loading...
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精製度
Affinity purified -
ポリ/モノ
モノクローナル -
クローン名
DTA-1 -
アイソタイプ
IgG2b -
軽鎖の種類
lambda -
研究分野
関連製品
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab72404の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
ab136125 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use at an assay dependent concentration. ab136125 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. -
組織特異性
Expressed in lymph node, peripheral blood leukocytes and weakly in spleen. -
配列類似性
Contains 3 TNFR-Cys repeats. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 21936 Mouse
- SwissProt: O35714 Mouse
- Unigene: 482508 Mouse
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別名
- Activation inducible TNFR family receptor antibody
- Activation-inducible TNFR family receptor antibody
- AITR antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (1)
ab72404 は 1 報の論文で使用されています。
- Zhou Y et al. MicroRNA-30a controls the instability of inducible CD4+ Tregs through SOCS1. Mol Med Rep 20:4303-4314 (2019). PubMed: 31545427