製品の概要

  • 製品名
    Anti-TNFRSF14 antibody [MM0332-5S1]
    TNFRSF14 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MM0332-5S1] to TNFRSF14
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment corresponing to the extracellular domain of Human TNFRSF14

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89479 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Predicted molecular weight: 30 kDa.
IHC-P 1/20 - 1/100.

ターゲット情報

  • 機能
    Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
  • 組織特異性
    Widely expressed, with the highest expression in lung, spleen and thymus.
  • 配列類似性
    Contains 3 TNFR-Cys repeats.
  • 翻訳後修飾
    N-glycosylated.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • HVEML antibody
    • ATAR antibody
    • CD270 antibody
    • CD40 like protein precursor antibody
    • Herpes virus entry mediator A antibody
    • Herpesvirus entry mediator A antibody
    • Herpesvirus entry mediator antibody
    • Herpesvirus entry mediator ligand antibody
    • HveA antibody
    • HVEM antibody
    • HVEM L antibody
    • LIGHT antibody
    • LIGHTR antibody
    • TNFRSF14 antibody
    • TNFSF 14 antibody
    • TNR14_HUMAN antibody
    • TR2 antibody
    • Tumor necrosis factor receptor like gene2 antibody
    • Tumor necrosis factor receptor superfamily member 14 antibody
    • Tumor necrosis factor receptor superfamily member 14 precursor antibody
    • Tumor necrosis factor receptor-like 2 antibody
    see all

参考文献

This product has been referenced in:
  • Ramsay AG  et al. Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer. Blood 120:1412-21 (2012). IHC ; Human . Read more (PubMed: 22547582) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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