製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to TNFRSF14
  • アプリケーション
    適用あり: WB, IHC-P, ICCmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to 16 amino acids from near the C terminus of Human TNFRSF14.

  • ポジティブ・コントロール
    • Human Brain, Cortex tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 2 µg/ml. Predicted molecular weight: 30 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC Use at an assay dependent concentration.

ターゲット情報

  • 機能
    Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
  • 組織特異性
    Widely expressed, with the highest expression in lung, spleen and thymus.
  • 配列類似性
    Contains 3 TNFR-Cys repeats.
  • 翻訳後修飾
    N-glycosylated.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • HVEML antibody
    • ATAR antibody
    • CD270 antibody
    • CD40 like protein precursor antibody
    • Herpes virus entry mediator A antibody
    • Herpesvirus entry mediator A antibody
    • Herpesvirus entry mediator antibody
    • Herpesvirus entry mediator ligand antibody
    • HveA antibody
    • HVEM antibody
    • HVEM L antibody
    • LIGHT antibody
    • LIGHTR antibody
    • TNFRSF14 antibody
    • TNFSF 14 antibody
    • TNR14_HUMAN antibody
    • TR2 antibody
    • Tumor necrosis factor receptor like gene2 antibody
    • Tumor necrosis factor receptor superfamily member 14 antibody
    • Tumor necrosis factor receptor superfamily member 14 precursor antibody
    • Tumor necrosis factor receptor-like 2 antibody
    see all

画像

  • ab115544, at 5µg/ml, staining TNFRSF14 in Formalin-fixed, Paraffin-embedded Human Brain, cortex tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

参考文献

ab115544 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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