製品の概要

  • 製品名Anti-TNF Receptor I antibody
    TNF Receptor I 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TNF Receptor I
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Mouse, Rat, Sheep, Rabbit, Hamster, Cow, Dog, Human, Pig, Saccharomyces cerevisiae, Xenopus laevis, Drosophila melanogaster, Monkey
  • 免疫原

    Synthetic peptide derived from the sequence of mouse TNF Receptor 1

  • ポジティブ・コントロール
    • Mouse brain, Rat brain, HeLa (heat shocked) or Jurkat membrane lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab90463 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IP
  • 追加情報IP: Use at a concentration of 12.5 µg/ml.
    WB (ECL): 1/1000. Predicted molecular weight: 51 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
    • 関連疾患Familial hibernian fever
      Multiple sclerosis 5
    • 配列類似性Contains 1 death domain.
      Contains 4 TNFR-Cys repeats.
    • ドメインThe domain that induces A-SMASE is probably identical to the death domain. The N-SMASE activation domain (NSD) is both necessary and sufficient for activation of N-SMASE.
      Both the cytoplasmic membrane-proximal region and the C-terminal region containing the death domain are involved in the interaction with TRPC4AP.
    • 翻訳後修飾The soluble form is produced from the membrane form by proteolytic processing.
    • 細胞内局在Cell membrane. Golgi apparatus membrane. Secreted. A secreted form is produced through proteolytic processing and Secreted. Lacks a Golgi-retention motif, is not membrane bound and therefore is secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD120a antibody
      • FPF antibody
      • MGC19588 antibody
      • p55 antibody
      • p55-R antibody
      • p60 antibody
      • TBP1 antibody
      • TBPI antibody
      • TNF R antibody
      • TNF R55 antibody
      • TNF-R1 antibody
      • TNF-RI antibody
      • TNFAR antibody
      • TNFR-I antibody
      • TNFR1 antibody
      • TNFR55 antibody
      • TNFR60 antibody
      • TNFRI antibody
      • TNFRSF1a antibody
      • TNR1A_HUMAN antibody
      • Tumor necrosis factor receptor 1 antibody
      • Tumor necrosis factor receptor superfamily, member 1A antibody
      • Tumor necrosis factor receptor type 1 antibody
      • Tumor necrosis factor receptor type I antibody
      • Tumor necrosis factor-binding protein 1 antibody
      see all

    Anti-TNF Receptor I antibody 画像

    • All lanes : Anti-TNF Receptor I antibody (ab90463) at 1/1000 dilution

      Lane 1 : HeLa (heat shocked) cell extract
      Lane 2 : Jurkat cell extract


      Predicted band size : 51 kDa

    Anti-TNF Receptor I antibody (ab90463) 使用論文

    ab90463 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab90463.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"