製品の概要

  • 製品名Anti-TNF beta antibody [EP1113Y]
    TNF beta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EP1113Y] to TNF beta
  • アプリケーション適用あり: WBmore details
    適用なし: IP
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to residues near the N term of TNF beta (Human)

  • ポジティブ・コントロール
    • Recombinant TNF beta
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab52639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/5000. Detects a band of approximately 18 kDa (predicted molecular weight: 22 kDa).
  • 追加情報Is unsuitable for IP.
  • ターゲット情報

    • 機能Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
    • 関連疾患Genetic variations in LTA are a cause of susceptibility psoriatic arthritis (PSORAS) [MIM:607507]. PSORAS is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoidlike pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis).
    • 配列類似性Belongs to the tumor necrosis factor family.
    • 細胞内局在Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated.
    • Information by UniProt
    • 参照データベース
    • 別名
      • LTalpha antibody
      • DIF antibody
      • LT alpha antibody
      • LT antibody
      • LT-alpha antibody
      • Lta antibody
      • Lymphotoxin alpha (TNF superfamily, member 1) antibody
      • Lymphotoxin alpha antibody
      • Lymphotoxin-alpha antibody
      • TNF B antibody
      • TNF superfamily member 1 antibody
      • TNF, lymphocyte-derived antibody
      • TNF-beta antibody
      • TNFB antibody
      • TNFB_HUMAN antibody
      • TNFbeta antibody
      • TNFSF1 antibody
      • TNLG1E antibody
      • Tumor necrosis factor beta antibody
      • tumor necrosis factor ligand 1E antibody
      • Tumor necrosis factor ligand superfamily member 1 antibody
      see all

    Anti-TNF beta antibody [EP1113Y] 画像

    • Anti-TNF beta antibody [EP1113Y] (ab52639) at 1/5000 dilution + Recombinant TNF beta at 0.05 µg

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 22 kDa
      Observed band size : 18 kDa (why is the actual band size different from the predicted?)

    Anti-TNF beta antibody [EP1113Y] (ab52639) 使用論文

    ab52639 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab52639.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"