製品の概要

  • 製品名Anti-TNF alpha antibody
    TNF alpha 一次抗体 製品一覧
  • 製品の詳細
    Chicken polyclonal to TNF alpha
  • アプリケーション適用あり: ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment corresponding to Human TNF alpha aa 77-233.
    Database link: P01375

  • ポジティブ・コントロール
    • Recombinant TNF alpha.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab26850 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use a concentration of 0.1 µg/ml.

ターゲット情報

  • 機能Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
  • 関連疾患Genetic variations in TNF are a cause of susceptibility psoriatic arthritis (PSORAS) [MIM:607507]. PSORAS is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoidlike pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis).
  • 配列類似性Belongs to the tumor necrosis factor family.
  • 翻訳後修飾The soluble form derives from the membrane form by proteolytic processing.
    The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1.
    O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.
  • 細胞内局在Secreted and Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • APC1 antibody
    • APC1 protein antibody
    • Cachectin antibody
    • DIF antibody
    • Differentiation inducing factor antibody
    • Macrophage cytotoxic factor antibody
    • Tnf antibody
    • TNF superfamily, member 2 antibody
    • TNF, macrophage derived antibody
    • TNF, monocyte derived antibody
    • TNF-a antibody
    • TNF-alpha antibody
    • TNFA antibody
    • TNFA_HUMAN antibody
    • TNFSF2 antibody
    • Tumor necrosis factor alpha antibody
    • Tumor necrosis factor antibody
    • Tumor necrosis factor ligand superfamily member 2 antibody
    • Tumor Necrosis Factor, Membrane Form antibody
    • Tumor necrosis factor, soluble form antibody
    see all

Anti-TNF alpha antibody 画像

  • Direct ELISA test detecting recombinant TNF alpha using 0.1 µg/ml ab26850 and a rabbit anti IgY HRP as secondary antibody.

Anti-TNF alpha antibody (ab26850) 使用論文

ab26850 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your phone call. I have created the new order #978640 with ab8348. The order will be dispatched on Monday for Tuesday delivery. I hope the antibody will work fine. Should you have any other question please do not hesitate to ask.

Thank you for your phone call. The antibody ab9635 which was used as a detection antibody and antibody ab8348 as capture antibody. These antibodies were tested as match pairs so these are fully guaranteed to work in sELISA. you can use ab6721 w...

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Thank you for contacting us. You had spoken to my colleague Karin; she is out of office for few weeks so I will be dealing with this case now on. I have read the whole protocol you have kindly provided and want to make few comments and suggesti...

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Thank you for contacting us and reporting the problems you are experiencing with this product. Thank you for contacting us. We take product complaints very seriously, and investigate every product that we feel may not be performing correctly. As ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"