製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to TMPRSS5
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide:

    LDWIHDTAQDSLL

    , corresponding to C terminal amino acids 445-457 of Human TMPRSS5

  • 特記事項
    Principal Names - TMPRSS5; transmembrane protease, serine 5 (spinesin); SPINESIN; spinesin. Official Gene Symbol - TMPRSS5. GenBank Accession Number – NP_110397. LocusLink ID - 80975

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
  • Concentration information loading...
  • 精製度
    IgG fraction
  • 特記事項(精製)
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab2245 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報
    WB: Use at a concentration of 1 - 3 µg/ml. Detects two bands of approximately 35 and 52 kDa in mouse brain lysate.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      May play a role in hearing.
    • 組織特異性
      Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord.
    • 関連疾患
      Note=Defects in TMPRSS5 may be a cause of deafness.
    • 配列類似性
      Belongs to the peptidase S1 family.
      Contains 1 peptidase S1 domain.
      Contains 1 SRCR domain.
    • 細胞内局在
      Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • MGC141886 antibody
      • MGC148044 antibody
      • OTTHUMP00000238209 antibody
      • OTTHUMP00000238210 antibody
      • OTTHUMP00000238211 antibody
      • OTTHUMP00000238212 antibody
      • OTTHUMP00000238213 antibody
      • Spinesin antibody
      • TMPRSS 5 antibody
      • TMPRSS5 antibody
      • TMPS5_HUMAN antibody
      • Transmembrane protease serine 5 antibody
      • Transmembrane protease, serine 5 (spinesin) antibody
      • Transmembrane protease, serine 5 antibody
      see all

    画像

    • ab2245 staining (2µg/ml) of Mouse Brain lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
    • ab2245 staining (0.5µg/ml) of Human Brain (Cerebral Cortex) lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

    プロトコール

    参考文献

    This product has been referenced in:

    See 1 Publication for this product

    レビューと Q&A

    Thank you for your enquiry and your patience, the source of ab2245 has confirmed that Western blots were done using reducing conditions. The exact protocol is below: - SDS PAGE. Samples were run at 200V constant on a 12% acrylamide SDS-PAGE min...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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