製品の概要

  • 製品名Anti-TMPRSS3 antibody
    TMPRSS3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to TMPRSS3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: VFTAASWKTM CSDDWKGHYA NVACAQLGFP SYVSSDNLRV SSLEGQFREE FVSIDHLLPD DKVTALHHSV YVREGCASGH VVTLQCTACG HRRGYS, corresponding to amino acids 119-215 of Human TMPRSS3

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57566 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro).
    • 組織特異性Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.
    • 関連疾患Defects in TMPRSS3 are the cause of deafness autosomal recessive type 8 (DFNB8) [MIM:601072]. DFNA8 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
      Defects in TMPRSS3 are the cause of deafness autosomal recessive type 10 (DFNB10) [MIM:605316].
    • 配列類似性Belongs to the peptidase S1 family.
      Contains 1 LDL-receptor class A domain.
      Contains 1 peptidase S1 domain.
      Contains 1 SRCR domain.
    • 翻訳後修飾Undergoes autoproteolytic activation.
    • 細胞内局在Endoplasmic reticulum membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Deafness autosomal recessive 10 antibody
      • DFNB10 antibody
      • DFNB8 antibody
      • ECHOS1 antibody
      • Gene similar to transmembrane serine protease antibody
      • MGC130589 antibody
      • Serine protease TADG-12 antibody
      • si:dz69g10.3 antibody
      • TADG12 antibody
      • TMPRSS 3 antibody
      • TMPRSS3 antibody
      • TMPS3_HUMAN antibody
      • Transmembrane protease serine 3 antibody
      • Tumor associated differentially expressed gene 12 protein antibody
      • Tumor-associated differentially-expressed gene 12 protein antibody
      • UNQ323/PRO382 antibody
      see all

    Anti-TMPRSS3 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57566 TMPRSS3 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-TMPRSS3 antibody (ab57566) 使用論文

    ab57566 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57566.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"