製品の概要

  • 製品名Anti-TMPRSS3 antibody
    TMPRSS3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TMPRSS3
  • 特異性This antibody reacts specifically with human TMPRSS3.
  • アプリケーション適用あり: WBmore details
  • 免疫原

    A 15 residue synthetic peptide derived from specific domain of human TMPRSS3 protein.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab24158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Predicted molecular weight: 49 kDa.

ターゲット情報

  • 機能Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro).
  • 組織特異性Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.
  • 関連疾患Defects in TMPRSS3 are the cause of deafness autosomal recessive type 8 (DFNB8) [MIM:601072]. DFNA8 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
    Defects in TMPRSS3 are the cause of deafness autosomal recessive type 10 (DFNB10) [MIM:605316].
  • 配列類似性Belongs to the peptidase S1 family.
    Contains 1 LDL-receptor class A domain.
    Contains 1 peptidase S1 domain.
    Contains 1 SRCR domain.
  • 翻訳後修飾Undergoes autoproteolytic activation.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt
  • 別名
    • Deafness autosomal recessive 10 antibody
    • DFNB10 antibody
    • DFNB8 antibody
    • ECHOS1 antibody
    • Gene similar to transmembrane serine protease antibody
    • MGC130589 antibody
    • Serine protease TADG-12 antibody
    • si:dz69g10.3 antibody
    • TADG12 antibody
    • TMPRSS 3 antibody
    • TMPRSS3 antibody
    • TMPS3_HUMAN antibody
    • Transmembrane protease serine 3 antibody
    • Tumor associated differentially expressed gene 12 protein antibody
    • Tumor-associated differentially-expressed gene 12 protein antibody
    • UNQ323/PRO382 antibody
    see all

Anti-TMPRSS3 antibody 画像

  • All lanes : Anti-TMPRSS3 antibody (ab24158)

    Lane 1 : total extract from 293T cells transfected with pHATMPRSS3
    Lane 2 : total extract from 293T cells transfected with pHA (empty vector)

    Lysates/proteins at 40 µg per lane.


    Predicted band size : 49 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

Anti-TMPRSS3 antibody (ab24158) 使用論文

ab24158 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your patience. I heard back from the lab regarding ab24158:  There is no homology with mouse. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Thank you for your enquiry. This product was raised in rabbit against a mixture of two synthetic peptides : NH2-MGENDPPAVEAPFSFC-COOH (amino acids 1-16 of human TMPRSS3) and NH2-CFLDWIHEQMERDLKT-COOH (amino acids 439-454of human TMPRSS3). As we a...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"