製品の概要

  • 製品名Anti-TMEM49 antibody
    TMEM49 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to TMEM49
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human protein

  • ポジティブ・コントロール
    • TMEM49 transfected 293T lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab69224 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 47 kDa (predicted molecular weight: 47 kDa).

ターゲット情報

  • 機能Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions.
  • 配列類似性Belongs to the VMP1 family.
  • 細胞内局在Endoplasmic reticulum-Golgi intermediate compartment membrane. Cell membrane. Vacuole membrane. Endoplasmic reticulum.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZP566I133 antibody
    • ectopic P-granules autophagy protein 3 homolog antibody
    • NF E2 induceble protein 2 antibody
    • NF E2 inducible protein 2 antibody
    • ni 2 antibody
    • protein ni 2 antibody
    • Tango5 antibody
    • TDC1 antibody
    • TMEM49 antibody
    • Transmembrane protein 49 antibody
    • transport and golgi organization 5 homolog antibody
    • Vacuole membrane protein 1 antibody
    • vmp1 antibody
    • VMP1_HUMAN antibody
    see all

Anti-TMEM49 antibody 画像

  • All lanes : Anti-TMEM49 antibody (ab69224) at 1/500 dilution

    Lane 1 : TMEM49 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 47 kDa
    Observed band size : 47 kDa

Anti-TMEM49 antibody (ab69224) 使用論文

This product has been referenced in:
  • Qu A  et al. Hypoxia-inducible MiR-210 is an independent prognostic factor and contributes to metastasis in colorectal cancer. PLoS One 9:e90952 (2014). WB ; Human . Read more (PubMed: 24632577) »
  • Lo Ré AE  et al. Novel AKT1-GLI3-VMP1 Pathway Mediates KRAS Oncogene-induced Autophagy in Cancer Cells. J Biol Chem 287:25325-34 (2012). WB ; Human . Read more (PubMed: 22535956) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"