製品の概要

  • 製品名Anti-TMEM43 antibody
    TMEM43 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TMEM43
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids 194-223 of Human TMEM43 (NP_077310.1).

  • ポジティブ・コントロール
    • MDA-MB231 cell line lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113116 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 45 kDa.

ターゲット情報

  • 機能May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane.
  • 組織特異性Highest expression in placenta. Also found at lower levels in heart, ovary, spleen, small intestine, thymus, prostate and testis.
  • 関連疾患Defects in TMEM43 are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5) [MIM:604400]; also known as arrhythmogenic right ventricular cardiomyopathy (ARVC5). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
  • 配列類似性Belongs to the TMEM43 family.
  • 細胞内局在Endoplasmic reticulum. Nucleus inner membrane. Retained in the inner nuclear membrane through interaction with EMD and A-and B-lamins. The N- and C-termini are orientated towards the nucleoplasm. The majority of the hydrophilic domain resides in the endoplasmic reticulum lumen.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ARVC5 antibody
    • ARVD5 antibody
    • EDMD7 antibody
    • LUMA antibody
    • Protein LUMA antibody
    • Tmem43 antibody
    • TMM43_HUMAN antibody
    • Transmembrane protein 43 antibody
    see all

Anti-TMEM43 antibody 画像

  • Anti-TMEM43 antibody (ab113116) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

    Predicted band size : 45 kDa

Anti-TMEM43 antibody (ab113116) 使用論文

ab113116 has not yet been referenced specifically in any publications.

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Please note you do not need the above code to place the initial order for ab113116. You only need it to redeem your free primary antibody after you have submitted your Abreview relating your experience testing ab113116 with mouse samples.
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