製品の概要

  • 製品名Anti-TMEFF2 antibody
    TMEFF2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to TMEFF2
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Mouse, Cow, Human
  • 免疫原

    Recombinant fragment: SYDNACQIKE ASCQKQEKIE VMSLGRCQDN TTTTTKSEDG HYARTDYAEN ANKLEESARE HHIPCPEHYN GFCMHGKCEH SINMQEPSCR CD, corresponding to amino acids 201-292 of Human TMEFF2 protein (NP_057276)

  • ポジティブ・コントロール
    • Recombinant tagged human TMEFF2 protein fragment (the immunogen)

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77038 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: Use at an assay dependent dilution.
    WB: 1/500 - 1/1000. Predicted molecular weight: 41 kDa.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.
    • 組織特異性Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate.
    • 配列類似性Belongs to the tomoregulin family.
      Contains 1 EGF-like domain.
      Contains 2 Kazal-like domains.
    • 翻訳後修飾N-glycosylated. Contains chondroitin sulfate glycosaminoglycans.
      A soluble form (TMEFF2-ECD) is produced by proteolytic shedding. This shedding can be induced by phorbol ester or proinflammatory cytokines such as TNFalpha, and is mediated by ADAM17.
    • 細胞内局在Secreted and Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Cancer/testis antigen family 120 member 2 antibody
      • CT120.2 antibody
      • HPP 1 antibody
      • HPP1 antibody
      • Hyperplastic polyposis protein 1 antibody
      • TEFF 2 antibody
      • TEFF2 antibody
      • TEFF2_HUMAN antibody
      • TENB 2 antibody
      • TENB2 antibody
      • TMEFF2 antibody
      • Tomoregulin antibody
      • Tomoregulin-2 antibody
      • TPEF antibody
      • TR 2 antibody
      • TR antibody
      • TR-2 antibody
      • Transmembrane protein containing epidermal growth factor and follistatin domains antibody
      • Transmembrane protein TENB2 antibody
      • Transmembrane protein with EGF like and two follistatin like domains 2 antibody
      • Transmembrane protein with EGF-like and two follistatin-like domains antibody
      see all

    Anti-TMEFF2 antibody 画像

    • Anti-TMEFF2 antibody (ab77038) at 1/500 dilution + recombinant tagged human TMEFF2 protein (the immunogen) at 0.2 µg

      Secondary
      Goat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

      Predicted band size : 41 kDa
      Observed band size : 41 kDa

    Anti-TMEFF2 antibody (ab77038) 使用論文

    ab77038 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab77038.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"