製品の概要
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製品名Anti-TMC6 antibody
TMC6 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to TMC6
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由来種Rabbit
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アプリケーション適用あり: ICC/IF, WB, IHC-Pmore details
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種交差性交差種: Mouse, Rat, Human
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免疫原
a 14 amino acid synthetic peptide from near the amino terminus of human TMC6.
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ポジティブ･コントロール
- A20 cell lysate
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: PBS -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab67325 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF | Use at an assay dependent concentration. | |
| WB | Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 90 kDa). | |
| IHC-P | Use a concentration of 2.5 µg/ml. |
ターゲット情報
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関連性Defects in TMC6 are a cause of epidermodysplasia verruciformis, a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions. TMC6 is expressed in placenta, prostate, testis, activated T-lymphocytes and lymphokine-activated killer (LAK) lymphocytes. There are four named isoforms.
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細胞内局在Endoplasmic reticulum membrane; Multi-pass membrane protein
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参照データベース
- Entrez Gene: 11322 Human
- Entrez Gene: 217353 Mouse
- Omim: 605828 Human
- SwissProt: Q7Z403 Human
- SwissProt: Q7TN60 Mouse
- Unigene: 632227 Human
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別名
- Epidermodysplasia verruciformis protein 1 antibody
- EV1 antibody
- EVER1 antibody
see all
画像
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Western blot - TMC6 antibody (ab67325)Lane 1 : Anti-TMC6 antibody (ab67325) at 1 µg/ml
Lane 2 : Anti-TMC6 antibody (ab67325) at 2 µg/ml
All lanes : A20 cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 90 kDa
Observed band size: 90 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TMC6 antibody (ab67325)ab67325 at 2.5 µg/ml staining TMC6 in human spleen tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).
プロトコール
参考文献
ab67325 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"