製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to TMC6
  • アプリケーション
    適用あり: ICC/IF, WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    a 14 amino acid synthetic peptide from near the amino terminus of human TMC6.

  • ポジティブ・コントロール
    • A20 cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab67325 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent concentration.
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 90 kDa).
IHC-P Use a concentration of 2.5 µg/ml.

ターゲット情報

  • 関連性
    Defects in TMC6 are a cause of epidermodysplasia verruciformis, a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions. TMC6 is expressed in placenta, prostate, testis, activated T-lymphocytes and lymphokine-activated killer (LAK) lymphocytes. There are four named isoforms.
  • 細胞内局在
    Endoplasmic reticulum membrane; Multi-pass membrane protein
  • 参照データベース
  • 別名
    • Epidermodysplasia verruciformis protein 1 antibody
    • EV1 antibody
    • EVER1 antibody
    • EVIN1 antibody
    • LAK 4P antibody
    • LAK4P antibody
    • Protein LAK 4 antibody
    • Protein LAK4 antibody
    • Transmembrane channel like protein 6 antibody
    see all

画像

  • Lane 1 : Anti-TMC6 antibody (ab67325) at 1 µg/ml
    Lane 2 : Anti-TMC6 antibody (ab67325) at 2 µg/ml

    Lane 1 : A20 cell lysate
    Lane 2 : A20 cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 90 kDa
    Observed band size : 90 kDa
  • ab67325 at 2.5 µg/ml staining TMC6 in human spleen tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).

参考文献

ab67325 has not yet been referenced specifically in any publications.

レビューと Q&A

Application
Immunocytochemistry/ Immunofluorescence
Sample
Chinese Hamster Cell (CHO)
Specification
CHO
Fixative
Formaldehyde
Permeabilization
Yes - triton
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10µg/mL · Temperature: 25°C
Username

Abcam user community

Verified customer

投稿 Apr 15 2013

Thank you for your inquiry.

Unfortunately, we are not able to release the immunogen sequence for ab67325 and ab69859 as it is proprietary information.

However, I can tell you that ab67325 is against a peptide from within xxxxx of ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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