製品の概要

  • 製品名Anti-TLR9 antibody
    TLR9 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TLR9
  • アプリケーション適用あり: ICC, WB, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to 15 amino acids near the center of human TLR9

  • ポジティブ・コントロール
    • Jurkat cells and cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab62577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC Use a concentration of 2 µg/ml.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 115 kDa).
ICC/IF Use a concentration of 20 µg/ml.

ターゲット情報

  • 機能Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • 組織特異性Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.
  • 配列類似性Belongs to the Toll-like receptor family.
    Contains 26 LRR (leucine-rich) repeats.
    Contains 1 TIR domain.
  • 細胞内局在Endoplasmic reticulum membrane. Endosome. Lysosome. Cytoplasmic vesicle > phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 289 antibody
    • CD289 antibody
    • TLR 9 antibody
    • TLR9 antibody
    • TLR9_HUMAN antibody
    • Toll like receptor 9 antibody
    • Toll like receptor 9 isoform A precursor antibody
    • Toll like receptor 9 isoform B antibody
    • Toll-like receptor 9 antibody
    see all

Anti-TLR9 antibody 画像

  • ab62577 at 2µg/ml staining TLR9 in Jurkat cells by Immunocytochemistry.
  • Lane 1 : Anti-TLR9 antibody (ab62577) at 0.5 µg/ml
    Lane 2 : Anti-TLR9 antibody (ab62577) at 1 µg/ml
    Lane 3 : Anti-TLR9 antibody (ab62577) at 2 µg/ml

    Lane 1 : Jurkat cell lysate
    Lane 2 : Jurkat cell lysate
    Lane 3 : Jurkat cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 115 kDa
    Observed band size : 95 kDa (why is the actual band size different from the predicted?)
  • Immunofluorescence of TLR9 in Mouse Spleen cells using ab62577 at 10 ug/ml.

Anti-TLR9 antibody (ab62577) 使用論文

ab62577 has not yet been referenced specifically in any publications.

Product Wall

I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused. As requested, I have issued a free of charge replacement for one vial of ab62577.
To check the status of the order please contact our Cus...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"