製品の概要

  • 製品名Anti-TLR8 antibody
    TLR8 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to TLR8
  • アプリケーション適用あり: WB, ICC, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide:

    CESFQGLQNLTKINLNHNPNVQHQNGNPGI

    , corresponding to amino acids 81-109 of Human TLR8

  • ポジティブ・コントロール
    • Mouse spleen and human tonsil tissue.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab53630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 119 kDa.
ICC 1/400. Acetone fixed.
IHC-P Use at an assay dependent dilution.

ターゲット情報

  • 機能Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • 組織特異性Detected in brain, heart, lung, liver, placenta, in monocytes, and at lower levels in CD11c+ immature dendritic cells.
  • 配列類似性Belongs to the Toll-like receptor family.
    Contains 23 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 288 antibody
    • CD288 antibody
    • CD288 antigen antibody
    • MGC119599 antibody
    • MGC119600 antibody
    • TLR 8 antibody
    • Tlr8 antibody
    • TLR8_HUMAN antibody
    • Toll like receptor 8 antibody
    • Toll-like receptor 8 antibody
    see all

Anti-TLR8 antibody 画像

  • ab53630 at 1/250 dilution staining TLR8 in mouse spleen by Immunohistochemistry, Paraffin embedded tissue.
  • ab53630 at 1/250 dilution staining TLR8 in human tonsil by Immunohistochemistry, Paraffin embedded tissue.

Anti-TLR8 antibody (ab53630) 使用論文

This product has been referenced in:
  • Thiyagarajan D  et al. Silencing of Renal DNaseI in Murine Lupus Nephritis Imposes Exposure of Large Chromatin Fragments and Activation of Toll Like Receptors and the Clec4e. PLoS One 7:e34080 (2012). Read more (PubMed: 22479529) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab53630.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"