製品の概要

  • 製品名Anti-TLR8 antibody [44C143]
    TLR8 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [44C143] to TLR8
  • アプリケーション適用あり: WB, IHC-P, Flow Cytmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within amino acids 750-850 of Human TLR8

  • ポジティブ・コントロール
    • Human brain cortex, Human spleen, 293 transfected with human TLR8, and Ramos cells

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab85859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 120 kDa.
IHC-P Use a concentration of 5 µg/ml.
Flow Cyt Use 0.5µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • 組織特異性Detected in brain, heart, lung, liver, placenta, in monocytes, and at lower levels in CD11c+ immature dendritic cells.
  • 配列類似性Belongs to the Toll-like receptor family.
    Contains 23 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 288 antibody
    • CD288 antibody
    • CD288 antigen antibody
    • MGC119599 antibody
    • MGC119600 antibody
    • TLR 8 antibody
    • Tlr8 antibody
    • TLR8_HUMAN antibody
    • Toll like receptor 8 antibody
    • Toll-like receptor 8 antibody
    see all

Anti-TLR8 antibody [44C143] 画像

  • ab85859 at 5 µg/ml staining TLR8 in formalin fixed and paraffin embedded brain cortex
  • ab85859 at 5 µg/ml staining TLR8 in formalin fixed and paraffin embedded spleen tissue
  • Anti-TLR8 antibody [44C143] (ab85859) at 2 µg/ml + 293 cell lysate transfected with Human TLR8

    Predicted band size : 120 kDa
    Observed band size : 120 kDa
  • ab85859 at 0.5µg in 1x106 Ramos cells
    Shaded histogram represents Ramos cells without antibody; green represents isotype control; purple represents TLR8 antibody.

Anti-TLR8 antibody [44C143] (ab85859) 使用論文

ab85859 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"