製品の概要

  • 製品名Anti-TLR7 antibody
    TLR7 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to TLR7
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: ARWFPKTLPC DVTLDVPKNH VIVDCTDKHL TEIPGGIPTN TTNLTLTINH IPDISPASFH RLDHLVEIDF RCNCVPIPLG SKNNMCIKRL QIKPRSFSGL T, corresponding to amino acids 27-127 of Human TLR7 (NP_057646) with a proprietary tag.

  • ポジティブ・コントロール
    • Daoy cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89509 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 121 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • 組織特異性Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.
  • 配列類似性Belongs to the Toll-like receptor family.
    Contains 27 LRR (leucine-rich) repeats.
    Contains 1 TIR domain.
  • 細胞内局在Endoplasmic reticulum membrane. Endosome. Lysosome. Cytoplasmic vesicle > phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
  • Information by UniProt
  • 参照データベース
  • 別名
    • PRO285 antibody
    • TLR 7 antibody
    • Tlr7 antibody
    • TLR7_HUMAN antibody
    • Toll like receptor 7 antibody
    • Toll-like receptor 7 antibody
    • UNQ248 antibody
    see all

Anti-TLR7 antibody 画像

  • Anti-TLR7 antibody (ab89509) at 5 µg/ml + Daoy cell lysate at 50 µg

    Predicted band size : 121 kDa
  • Anti-TLR7 antibody (ab89509) at 5 µg/ml + immunogen (101aa recombinant fragment with a tag of 26kDa) at 0.2 µg

    Predicted band size : 121 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)

Anti-TLR7 antibody (ab89509) 使用論文

ab89509 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab89509.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"