製品の概要

  • 製品名Anti-TLR7 antibody
    TLR7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TLR7
  • アプリケーション適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide (Mouse) corresponding to 14 amino acids near the middle of mouse TLR7.

  • ポジティブ・コントロール
    • Daudi cell lysates.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab24184 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 2 µg/ml.
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 122 kDa.

ターゲット情報

  • 機能Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • 組織特異性Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.
  • 配列類似性Belongs to the Toll-like receptor family.
    Contains 27 LRR (leucine-rich) repeats.
    Contains 1 TIR domain.
  • 細胞内局在Endoplasmic reticulum membrane. Endosome. Lysosome. Cytoplasmic vesicle > phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
  • Information by UniProt
  • 参照データベース
  • 別名
    • PRO285 antibody
    • TLR 7 antibody
    • Tlr7 antibody
    • TLR7_HUMAN antibody
    • Toll like receptor 7 antibody
    • Toll-like receptor 7 antibody
    • UNQ248 antibody
    see all

Anti-TLR7 antibody 画像

  • Lane 1 : Anti-TLR7 antibody (ab24184) at 0.5 µg/ml
    Lane 2 : Anti-TLR7 antibody (ab24184) at 1 µg/ml
    Lane 3 : Anti-TLR7 antibody (ab24184) at 2 µg/ml

    Lane 1 : Daudi cell lysates.
    Lane 2 : Daudi cell lysates.
    Lane 3 : Daudi cell lysates.


    Predicted band size : 122 kDa
  • ab24184 at 2µg/ml staining of TLR7 in Daudi cells by ICC/IF

Anti-TLR7 antibody (ab24184) 使用論文

This product has been referenced in:

See 1 Publication for this product

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