製品の概要

  • 製品名Anti-TLR6 antibody
    TLR6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TLR6
  • 特異性ab62569 does not recognize TLR1.
  • アプリケーション適用あり: ICC, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A peptide corresponding to 13 amino acids near the centre of human TLR6.

  • ポジティブ・コントロール
    • Jurkat cell lysate. Jurkat cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab62569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC Use a concentration of 2 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 92 kDa).

ターゲット情報

  • 機能Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.
  • 組織特異性Detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.
  • 配列類似性Belongs to the Toll-like receptor family.
    Contains 12 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • 細胞内局在Cell membrane. Cytoplasmic vesicle > phagosome membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD286 antibody
    • CD286 antigen antibody
    • TLR 6 antibody
    • Tlr6 antibody
    • TLR6_HUMAN antibody
    • Toll like receptor 6 precursor antibody
    • Toll-like receptor 6 antibody
    see all

Anti-TLR6 antibody 画像

  • Lane 1 : Anti-TLR6 antibody (ab62569) at 0.5 µg/ml
    Lane 2 : Anti-TLR6 antibody (ab62569) at 1 µg/ml
    Lane 3 : Anti-TLR6 antibody (ab62569) at 2 µg/ml

    Lane 1 : Jurkat cell lysate
    Lane 2 : Jurkat cell lysate
    Lane 3 : Jurkat cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 92 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 110 kDa. We are unsure as to the identity of these extra bands.
  • ab62569, at 2µg/ml, staining TLR6 in Jurkat cells by immunocytochemistry.

Anti-TLR6 antibody (ab62569) 使用論文

ab62569 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab62569.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"