製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to TLR10
  • アプリケーション
    適用あり: WB, ICC, IHC-P, Flow Cytmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cow
  • 免疫原

    Synthetic peptide: C HNRIQQLDLK TFEFNKELRY LDLSNNRLKS V, corresponding to amino acids 80-111 of Human TLR10

  • ポジティブ・コントロール
    • Human spleen and tonsil tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53631 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 94 kDa.
ICC 1/400. Use acetone fixed cells.
IHC-P 1/250.
Flow Cyt Use at an assay dependent concentration. PubMed: 22943429ab37373-Goat polyclonal IgG, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能
    Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • 組織特異性
    Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.
  • 配列類似性
    Belongs to the Toll-like receptor family.
    Contains 15 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 290 antibody
    • CD 290 antigen antibody
    • CD290 antibody
    • CD290 antigen antibody
    • MGC104967 antibody
    • MGC126398 antibody
    • MGC126399 antibody
    • OTTHUMP00000158729 antibody
    • OTTHUMP00000218162 antibody
    • TLR10 antibody
    • TLR10_HUMAN antibody
    • Toll like receptor 10 antibody
    • Toll-like receptor 10 antibody
    • UNQ315/PRO358 antibody
    see all

画像

  • ab53631 at 1/250 dilution staining TLR10 in human spleen by Immunohistochemistry, Paraffin embedded tissue.
  • ab53631 at 1/250 dilution staining TLR10 in human tonsil by Immunohistochemistry, Paraffin embedded tissue.

参考文献

This product has been referenced in:
  • Latorre E  et al. Listeria monocytogenes Inhibits Serotonin Transporter in Human Intestinal Caco-2 Cells. Microb Ecol 72:730-9 (2016). Read more (PubMed: 27488594) »
  • Chougule P  et al. Isolation and characterization of human primary enterocytes from small intestine using a novel method. Scand J Gastroenterol 47:1334-43 (2012). Flow Cyt ; Human . Read more (PubMed: 22943429) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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