製品の概要

  • 製品名Anti-TLR1 antibody [EPR2075]
    TLR1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR2075] to TLR1
  • アプリケーション適用あり: WB, IP, Flow Cytmore details
    適用なし: ICC or IHC-P
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to residues on the extracellular region of human TLR1

  • ポジティブ・コントロール
    • WB: Daudi and Ramos cell lysates. Flow Cyt: Daudi cells.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab68158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IP
Flow Cyt
  • 追加情報Flow Cyt: 1/60.
    IP: 1/40.
    WB: 1/1000 - 1/2000. Detects a band of approximately 90 and 125 kDa (predicted molecular weight: 90 kDa).

    Is unsuitable for ICC or IHC-P.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
    • 組織特異性Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
    • 配列類似性Belongs to the Toll-like receptor family.
      Contains 12 LRR (leucine-rich) repeats.
      Contains 1 LRRCT domain.
      Contains 1 TIR domain.
    • 細胞内局在Cell membrane. Cytoplasmic vesicle > phagosome membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD281 antibody
      • CD281 antigen antibody
      • KIAA0012 antibody
      • LPRS5 antibody
      • rsc786 antibody
      • TIL antibody
      • TIL. LPRS5 antibody
      • Tlr1 antibody
      • TLR1_HUMAN antibody
      • Toll (Drosophila) homolog antibody
      • Toll like receptor 1 antibody
      • Toll-like receptor 1 antibody
      • Toll/interleukin-1 receptor-like protein antibody
      see all

    Anti-TLR1 antibody [EPR2075] 画像

    • All lanes : Anti-TLR1 antibody [EPR2075] (ab68158) at 1/1000 dilution

      Lane 1 : Daudi cell lysate
      Lane 2 : Ramos cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 90 kDa
      Observed band size : 90 kDa
      Additional bands at : 125 kDa. We are unsure as to the identity of these extra bands.
    • Flow cytometric analysis of TLR1 in Daudi cells using ab68158 at 1/60 dilution (pink) or a rabbit IgG (green).

    Anti-TLR1 antibody [EPR2075] (ab68158) 使用論文

    ab68158 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab68158.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"