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RabMAb

Anti-TLK1 抗体 [EPR2886] (ab108987)

製品の概要

  • 製品名
    Anti-TLK1 antibody [EPR2886]
    TLK1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR2886] to TLK1
  • アプリケーション
    適用あり: WB, IP, Flow Cytmore details
    適用なし: ICC or IHC-P
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human TLK1 (UniProt Q9UKI8).

  • ポジティブ・コントロール
    • HeLa and A431 cell lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

     

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab108987 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 86 kDa (predicted molecular weight: 87 kDa).
IP 1/10 - 1/100.
Flow Cyt 1/100 - 1/500. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 追加情報
    Is unsuitable for ICC or IHC-P.
  • ターゲット情報

    • 機能
      Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.
    • 組織特異性
      Widely expressed. Present in fetal placenta, liver, kidney and pancreas but not heart or skeletal muscle. Also found in adult cell lines. Isoform 3 is ubiquitously expressed in all tissues examined.
    • 配列類似性
      Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
      Contains 1 protein kinase domain.
    • 細胞内局在
      Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • PKU beta antibody
      • PKU-beta antibody
      • serine threonine protein kinase antibody
      • Serine/threonine protein kinase tousled like 1 antibody
      • Serine/threonine-protein kinase tousled-like 1 antibody
      • SNARE protein kinase SNAK antibody
      • Tlk1 antibody
      • TLK1_HUMAN antibody
      • Tousled like kinase 1 antibody
      • Tousled-like kinase 1 antibody
      see all

    画像

    • All lanes : Anti-TLK1 antibody [EPR2886] (ab108987) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : A431 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit IgG at 1/2000 dilution

      Predicted band size : 87 kDa
      Observed band size : 86 kDa (why is the actual band size different from the predicted?)

    参考文献

    ab108987 has not yet been referenced specifically in any publications.

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab108987.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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