製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to TIPRL
  • アプリケーション
    適用あり: WBmore details
    適用なし: IP
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Rabbit, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residues 200 and 250 of human TIPRL (NP_690866.1)

  • ポジティブ・コントロール
    • HeLa, 293T and NIH3T3 whole cell lysates.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab71974 was affinity purified using an epitope specific to TIPRL immobilized on solid support.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab71974 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000 - 1/10000. Detects a band of approximately 29 kDa (predicted molecular weight: 32 kDa).
  • 追加情報
    Is unsuitable for IP.
  • ターゲット情報

    • 機能
      May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.
    • 配列類似性
      Belongs to the TIP41 family.
    • 翻訳後修飾
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在
      Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 1810011K17Rik antibody
      • dJ69E11.3 antibody
      • MGC3794 antibody
      • Putative MAPK activating protein PM10 antibody
      • Putative MAPK-activating protein PM10 antibody
      • RP1-69E11.1 antibody
      • Tip antibody
      • TIP41 antibody
      • TIP41-like protein antibody
      • tiprl antibody
      • TIPRL_HUMAN antibody
      • TOR signaling pathway regulator antibody
      • TOR Signaling Pathway Regulator like antibody
      • Type 2A-interacting protein antibody
      see all

    画像

    • All lanes : Anti-TIPRL antibody (ab71974) at 0.04 µg/ml

      Lane 1 : HeLa whole cell lysate at 50 µg
      Lane 2 : HeLa whole cell lysate at 15 µg
      Lane 3 : HeLa whole cell lysate at 5 µg
      Lane 4 : 293T whole cell lysate at 50 µg
      Lane 5 : NIH3T3 whole cell lysate at 50 µg


      Predicted band size : 32 kDa
      Observed band size : 29 kDa (why is the actual band size different from the predicted?)


      Exposure time : 30 seconds

    プロトコール

    参考文献

    ab71974 has not yet been referenced specifically in any publications.

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