製品の概要

  • 製品名Anti-TIP30 antibody
    TIP30 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to TIP30
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide: AETEALSKLREDFR, corresponding to N terminal amino acids 2-15 of Human TIP30.

  • ポジティブ・コントロール
    • HeLa and human lung lysates.
  • 特記事項


    TIP30, also called CC3 or HTATIP2, is a putative metastasis suppressor that promotes apoptosis and inhibits angiogenesis. Although TIP30 has several characteristic features of a tumor suppressor in in vitro analyses, tumor development as a result of TIP30 inactivation has not been demonstrated in vivo, and abnormal expression of TIP30 in human cancer has not been reported.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab10268 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 28 kDa).Can be blocked with Human TIP30 peptide (ab23202).

ターゲット情報

  • 機能Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
  • 組織特異性Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas, 33% of hepatocellular carcinomas and neuroblastomas.
  • ドメインUnique C-terminus confers high proteasome-dependent instability to isoform 2.
  • 細胞内局在Cytoplasm. Nucleus envelope.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 30 kDa HIV 1 TAT interacting protein antibody
    • 30 kDa HIV-1 TAT-interacting protein antibody
    • 30 kDa HIV1 TAT interacting protein antibody
    • CC3 antibody
    • FLJ26963 antibody
    • HIV 1 Tat interacting protein 2 30kDa antibody
    • HIV 1 Tat interacting protein 2 antibody
    • HIV-1 TAT-interactive protein 2 antibody
    • HTAI2_HUMAN antibody
    • HTATIP 2 antibody
    • HTATIP2 antibody
    • Oxidoreductase HTATIP2 antibody
    • SDR44U1 antibody
    • Short chain dehydrogenase/reductase family 44U member 1 antibody
    • Tat interacting protein (30kDa) antibody
    see all

Anti-TIP30 antibody 画像



  • Predicted band size : 28 kDa


    ab10268 staining (1µg/ml) of human lung lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by Western blot using chemiluminescence.

Anti-TIP30 antibody (ab10268) 使用論文

ab10268 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"