製品の概要

  • 製品名Anti-Timeless antibody
    Timeless 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Timeless
  • 特異性ab51519 recognises the C terminal region of Timeless containing a SANT domain.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to Mouse Timeless aa 1178-1197 (C terminal).
    Sequence:

    SGTPRVHRKKRFQIEDEDD

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
  • Concentration information loading...
  • 精製度Protein A purified
  • 特記事項(精製)ab51519 was affinity purified on immobilized affinity based chromatography.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab51519 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Detects a band of approximately 139 kDa (predicted molecular weight: 139 kDa).
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localiZation. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.
  • 組織特異性Expressed in all tissues examined including brain, heart, lung, liver, skeletal muscle, kidney, placenta, pancreas, spleen, thymus and testis. Highest levels of expression in placenta, pancreas, thymus and testis.
  • 配列類似性Belongs to the timeless family.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ12640 antibody
    • FLJ20714 antibody
    • hTIM antibody
    • Protein timeless homolog antibody
    • TIM antibody
    • TIM_HUMAN antibody
    • TIM1 antibody
    • Timeless antibody
    • timeless circadian clock 1 antibody
    • timeless circadian clock antibody
    • timeless homolog antibody
    • TIMELESS1 antibody
    • Tof1 homolog antibody
    see all

Anti-Timeless antibody 画像

  • Anti-Timeless antibody (ab51519) at 1/500 dilution

    Predicted band size : 139 kDa
    Observed band size : 139 kDa

Anti-Timeless antibody (ab51519) 使用論文

ab51519 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"