Anti-TIM 1 抗体 (ab78494)
Key features and details
- Rabbit polyclonal to TIM 1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-TIM 1 antibody
TIM 1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TIM 1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human -
免疫原
Synthetic peptide, corresponding to a portion of the amino acids 200-300 of Human TIM 1
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ポジティブ・コントロール
- Testis tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: 0.05% BSA, PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab78494の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 39 kDa.
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IHC-P | (1) |
Use a concentration of 2.5 - 5 µg/ml.
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特記事項 |
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WB
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 39 kDa. |
IHC-P
Use a concentration of 2.5 - 5 µg/ml. |
ターゲット情報
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機能
May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. -
組織特異性
Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses. -
配列類似性
Belongs to the immunoglobulin superfamily. TIM family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 26762 Human
- Entrez Gene: 171283 Mouse
- Omim: 606518 Human
- SwissProt: Q96D42 Human
- SwissProt: Q5QNS5 Mouse
- Unigene: 129711 Human
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別名
- CD365 antibody
- HAVCR 1 antibody
- HAVCR antibody
see all
画像
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Immunohistochemical analysis of Formaldehyde-fixed murine obese nephric tissue sections, labelling TIM 1 with ab78494 at a dilution of 1/2500 incubated for 12 hours at 4°C in PBS and 2.5% Horse serum. Heat mediated antigen retrival was with Citrate buffer. Blocking was with 2.5% horse serum incubated for 1 hour at 25°C. Secondary was a horse anti-rabbit polyclonal HRP conjugate used undiluted. Counterstaining against nuclear DNA was with DAPI.
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue, staining TIM 1 with ab78494 at 5 µg/ml.
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All lanes : Anti-TIM 1 antibody (ab78494) at 3 µg/ml
Lane 1 : Human brain lysate
Lane 2 : Human brain lysate in presence of immunizing peptide
Lane 3 : Mouse brain lysate
Predicted band size: 39 kDa
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (10)
ab78494 は 10 報の論文で使用されています。
- Huang Q et al. Passively-targeted mitochondrial tungsten-based nanodots for efficient acute kidney injury treatment. Bioact Mater 21:381-393 (2023). PubMed: 36185743
- Wei X et al. Identification of Subtypes and a Delayed Graft Function Predictive Signature Based on Ferroptosis in Renal Ischemia-Reperfusion Injury. Front Cell Dev Biol 10:800650 (2022). PubMed: 35211472
- Standage SW et al. NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury. Am J Physiol Renal Physiol 320:F984-F1000 (2021). PubMed: 33843271
- Zhou Z et al. Correlation between serum carnosinase concentration and renal damage in diabetic nephropathy patients. Amino Acids 53:687-700 (2021). PubMed: 33811534
- Späth MR et al. The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int 95:333-349 (2019). PubMed: 30522767
- Yang X et al. Glucose-regulated protein 75 in foodborne disease models induces renal tubular necrosis. Food Chem Toxicol 133:110720 (2019). PubMed: 31369848
- Li YF et al. Protective effect of anisodamine in rats with glycerol-induced acute kidney injury. BMC Nephrol 20:223 (2019). PubMed: 31208365
- Zhang L et al. Effects of Farnesiferol B on Ischemia-Reperfusion-Induced Renal Damage, Inflammation, and NF-?B Signaling. Int J Mol Sci 20:N/A (2019). PubMed: 31842453
- Sureshbabu A et al. RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction. JCI Insight 3:N/A (2018). PubMed: 29875323
- Gai Z et al. Farnesoid X receptor activation protects the kidney from ischemia-reperfusion damage. Sci Rep 7:9815 (2017). PubMed: 28852062