製品の概要

  • 製品名Tiagabine hydrochloride
  • 製品の詳細
    Selective GAT-1 inhibitor
  • 別名
    • Gabitril
    • NNC 05-328
  • 生理活性の詳細GABA uptake inhibitor, selective for GAT-1. Anticonvulsant in vivo.

    Also available in simple stock solutions (ab146701) - add 1 ml of water to get an exact, ready-to-use concentration.
  • 精製度> 99%

製品の特性

    Tiagabine hydrochloride (ab120237) 使用論文

    This product has been referenced in:
    • Borden LA  et al. Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur J Pharmacol 269:219-24 (1994). Read more (PubMed: 7851497) »
    • Suzdak PD  et al. Quantitative autoradiographic characterization of the binding of [3H]tiagabine (NNC 05-328) to the GABA uptake carrier. Brain Res 647:231-41 (1994). Read more (PubMed: 7922499) »
    • Andersen KE  et al. The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate. J Med Chem 36:1716-25 (1993). Read more (PubMed: 8510100) »

    See all 2 Publications for this product

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