ab94248 is a 293T cell transfected lysate in which Human TIA1 has been transiently over-expressed using a pCMV-TIA1 plasmid. The lysate is provided in 1X Sample Buffer. Note: For more detailed how the transfected lysate was prepared view preparation notes
Function: Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
Similarity: Contains 3 RRM (RNA recognition motif) domains.