Anti-Thyroid Hormone Receptor alpha 1+2 抗体, prediluted (ab15544)

製品の概要

  • 製品名Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted
    Thyroid Hormone Receptor alpha 1+2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Thyroid Hormone Receptor alpha 1+2, prediluted
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Pig
  • 免疫原

    Synthetic peptide:

    DPEENSARSPDGKRKRKNGQ

    , corresponding to amino acids 13 to 32 of human TR alpha1 protein.

  • ポジティブ・コントロール
    • Colon carcinoma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab15544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: Use at an assay dependent dilution. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Isoform Alpha-1: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
      Isoform Alpha-2: Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action.
    • 関連疾患Hypothyroidism, congenital, non-goitrous, 6
    • 配列類似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • ドメインComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照���ータベース
    • 別名
      • c-erbA-1 antibody
      • C-erbA-alpha antibody
      • EAR-7 antibody
      • ERBA 1 antibody
      • ERBA antibody
      • ERBA related 7 antibody
      • Nuclear receptor subfamily 1 group A member 1 antibody
      • THA_HUMAN antibody
      • THRA antibody
      • Thra1 antibody
      • Thra2 antibody
      • Thyroid hormone receptor alpha 1 antibody
      • Thyroid hormone receptor alpha 2 antibody
      • Thyroid hormone receptor alpha antibody
      • TR alpha 1 antibody
      • TR alpha 2 antibody
      • Tra1 antibody
      • Triiodothyronine receptor antibody
      • V-erbA-related protein 7 antibody
      see all

    Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted 画像

    • ab15544 staining thyroid hormone receptor alpha 1 and 2 in colon carcinoma by Immunohistochemistry (formalin/paraffin).

    Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted (ab15544) 使用論文

    ab15544 has not yet been referenced specifically in any publications.

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