Anti-Thrombin Receptor 抗体 (ab111976)

製品の概要

  • 製品名Anti-Thrombin Receptor antibody
    Thrombin Receptor 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Thrombin Receptor
  • アプリケーション適用あり: WB, IHC-P, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    TRARRPESKATNAT

    by a Cysteine residue linker, corresponding to internal sequence amino acids 24-37 of Human Thrombin Receptor (NP_001983.2).

  • ポジティブ・コントロール
    • HeLa lysate; Human liver tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111976 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 47 kDa.
IHC-P Use a concentration of 2.5 µg/ml.
ELISA 1/3200.

ターゲット情報

  • 機能High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
  • 組織特異性Platelets and vascular endothelial cells.
  • 配列類似性Belongs to the G-protein coupled receptor 1 family.
  • 翻訳後修飾A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
    Phosphorylated; probably mediating desensitization prior to the uncoupling and internalization of the receptor.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CF2R antibody
    • Coagulation factor II (thrombin) receptor antibody
    • Coagulation factor II receptor antibody
    • F2R antibody
    • HTR antibody
    • PAR 1 antibody
    • PAR-1 antibody
    • PAR1 antibody
    • PAR1_HUMAN antibody
    • Protease activated receptor 1 antibody
    • Proteinase activated receptor 1 antibody
    • Proteinase-activated receptor 1 antibody
    • Thrombin receptor antibody
    • TR antibody
    see all

Anti-Thrombin Receptor antibody 画像

  • ab111976, at 2.5µg/ml, staining Thrombin Receptor in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.
  • Anti-Thrombin Receptor antibody (ab111976) at 0.5 µg/ml + HeLa lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 47 kDa

Anti-Thrombin Receptor antibody (ab111976) 使用論文

ab111976 has not yet been referenced specifically in any publications.

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The Uniprot http://www.uniprot.org/uniprot/P25116 database shows, the active part of protein "human Proteinase-activated receptor 1" has amino acid sequence between 42-425, so antibodies specific to this ...

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I am sorry this product did not perform as stated on the datasheet and for the inconvenience this h...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"