Anti-TGF beta induced factor 2 抗体 (ab39998)

製品の概要

  • 製品名
    Anti-TGF beta induced factor 2 antibody
    TGF beta induced factor 2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to TGF beta induced factor 2
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide:

    EMELQKQQDP

    , corresponding to C terminal amino acids 211-220 of Human TGF beta induced factor 2

  • ポジティブ・コントロール
    • A431, A549 and HEK293 cell lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab39998 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 26 kDa).
ELISA 1/16000.

ターゲット情報

  • 機能
    Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
  • 組織特異性
    Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate.
  • 配列類似性
    Belongs to the TALE/TGIF homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 翻訳後修飾
    The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway.
  • 細胞内局在
    Nucleus. Excluded from nucleoli.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5' TG 3' interacting factor 2 antibody
    • 5''-TG-3''-interacting factor 2 antibody
    • Homeobox protein TGIF2 antibody
    • TGF (beta) induced transcription factor 2 antibody
    • TGF-beta-induced transcription factor 2 antibody
    • TGFB induced factor 2 antibody
    • TGFB-induced factor 2 antibody
    • Tgif2 antibody
    • TGIF2_HUMAN antibody
    • Transforming growth factor beta induced factor 2 antibody
    see all

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プロトコール

参考文献

ab39998 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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