製品の概要

  • 製品名Anti-TGF beta 3 antibody
    TGF beta 3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TGF beta 3
  • 特異性Detects endogenous levels of total TGF ß3 protein.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from human TGF ß3.

  • ポジティブ・コントロール
    • Extracts from COS7 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 47 kDa.
ELISA 1/10000.

ターゲット情報

  • 機能Involved in embryogenesis and cell differentiation.
  • 関連疾患Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:107970]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
  • 配列類似性Belongs to the TGF-beta family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ARVD antibody
    • ARVD1 antibody
    • FLJ16571 antibody
    • MGC105479 antibody
    • MGC118722 antibody
    • prepro-transforming growth factor beta-3 antibody
    • RNHF antibody
    • TGF beta 3 antibody
    • TGF beta3 antibody
    • TGF-beta-3 antibody
    • TGFB 3 antibody
    • Tgfb3 antibody
    • TGFB3_HUMAN antibody
    • transforming growth factor beta 3 antibody
    • Transforming growth factor beta-3 antibody
    see all

Anti-TGF beta 3 antibody (ab53727) 使用論文

ab53727 has not yet been referenced specifically in any publications.

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ab9758 - the major band at44.3 kDa corresponding to the unprocessed (pre-pro-TGF beta 1) form, the mature processed TGF beta 1 is a 25 kD homodimer composed of two 12.5 kDa subunits joined by disulfide bonds. As th...

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The immunogen is 10aa long. The cross-reactivity against TGFb1 and TGFb2 has not been determined. However, the homology with the immunogen is 80% for both sequences. Thus, cross-reactivity could be possible.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"