製品の概要
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製品名Anti-TGF beta 3 antibody
TGF beta 3 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to TGF beta 3
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由来種Rabbit
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アプリケーション適用あり: WBmore details
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種交差性交差種: Human
交差が予測される動物種: Mouse, Rat, Horse, Dog, Chimpanzee, Macaque monkey, Gorilla, Chinese hamster, Orangutan
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免疫原
Synthetic peptide conjugated to KLH derived from within residues 250 - 350 of Human TGF beta 3.
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ポジティブ･コントロール
- This antibody gave a positive signal in Human Brain tissue lysate.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーpH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab113250 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Detects a band of approximately 47 kDa (predicted molecular weight: 47 kDa). Abcam recommends using milk as the blocking agent (3%). |
ターゲット情報
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機能Involved in embryogenesis and cell differentiation.
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関連疾患Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:107970]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
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配列類似性Belongs to the TGF-beta family.
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細胞内局在Secreted.
- Information by UniProt
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参照データベース
- Entrez Gene: 7043 Human
- Entrez Gene: 21809 Mouse
- Entrez Gene: 25717 Rat
- Omim: 190230 Human
- SwissProt: P10600 Human
- SwissProt: P17125 Mouse
- SwissProt: Q07258 Rat
- Unigene: 592317 Human
see all -
別名
- ARVD antibody
- ARVD1 antibody
- FLJ16571 antibody
see all
画像
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Western blot - Anti-TGF beta 3 antibody (ab113250)Anti-TGF beta 3 antibody (ab113250) at 1 µg/ml (Milk blocking - 3%) + Human brain tissue lysate - total protein (ab29466) at 20 µg
Secondary
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 47 kDa
Observed band size: 47 kDa
Exposure time: 8 minutes
Abcam recommends using milk as the blocking agent (3%). Abcam welcomes customer feedback and would appreciate any comments regarding this product and the data presented above.
プロトコール
参考文献
ab113250 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"