製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to TGF beta 2
  • 由来種
    Rabbit
  • 特異性
    ab81076 antibody reacts with the precursor and mature form of TGF beta 2 and to a lesser extent TGF beta 3, but does not cross react with TGF beta 1.
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide derived from the internal region of human TGF beta 2

  • ポジティブ・コントロール
    • Placenta

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab81076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報
    IHC-P: 1/100 for 30 min at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol, by boiling tissue sections in 10mM Citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.
    • 関連疾患
      A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.
      Loeys-Dietz syndrome 4
      Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features.
    • 配列類似性
      Belongs to the TGF-beta family.
    • 翻訳後修飾
      The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive.
    • 細胞内局在
      Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BSC-1 cell growth inhibitor antibody
      • BSC1 cell growth inhibitor antibody
      • Cetermin antibody
      • G-TSF antibody
      • Glioblastoma-derived T-cell suppressor factor antibody
      • GTSF antibody
      • LAP antibody
      • Latency-associated peptide antibody
      • MGC116892 antibody
      • MGF antibody
      • Milk growth factor antibody
      • Polyergin antibody
      • TGF-beta-2 antibody
      • TGF-beta2 antibody
      • TGFB2 antibody
      • TGFB2_HUMAN antibody
      • Transforming growth factor beta 2 antibody
      see all

    画像

    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human placenta tissue, using 1/100 ab81076.

    参考文献

    ab81076 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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