Anti-TFPI2 抗体 (ab86933)
Key features and details
- Rabbit polyclonal to TFPI2
- Suitable for: WB, IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-TFPI2 antibody
TFPI2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TFPI2 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Rat, Human
交差が予測される動物種: Mouse -
免疫原
A synthetic peptide corresponding to internal sequence of Human TFPI2
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ポジティブ・コントロール
- Rat brain and pancreas tissue lysates; MM453, MM231, HeLa, HT1080 and Jurkat whole cell lysates; Human mammary cancer tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservatives: 0.025% Sodium azide, 0.025% Thimerosal (merthiolate)
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab86933の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa.
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IHC-P |
Use a concentration of 2 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. |
IHC-P
Use a concentration of 2 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
ターゲット情報
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機能
May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. -
組織特異性
Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy. -
配列類似性
Contains 3 BPTI/Kunitz inhibitor domains. -
ドメイン
This inhibitor contains three inhibitory domains. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 7980 Human
- Entrez Gene: 21789 Mouse
- Entrez Gene: 286926 Rat
- Omim: 600033 Human
- SwissProt: P48307 Human
- SwissProt: O35536 Mouse
- Unigene: 438231 Human
- Unigene: 25612 Mouse
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別名
- Placental protein 5 antibody
- PP5 antibody
- REF1 antibody
see all
画像
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ab86933, at 2µg/ml, staining paraffin-embedded Human Mammary cancer tissue by Immunohistochemistry.
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All lanes : Anti-TFPI2 antibody (ab86933) at 1 µg/ml
Lane 1 : Rat brain tissue lysate
Lane 2 : Rat pancreas tissue lysate
Lane 3 : MM453 whole cell lysate
Lane 4 : MM231 whole cell lysate
Lane 5 : HeLa whole cell lysate
Lane 6 : HT1080 whole cell lysate
Lane 7 : Jurkat whole cell lysate
Predicted band size: 27 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab86933 は 2 報の論文で使用されています。
- Wang W et al. MicroRNA-23a acts as an oncogene in pancreatic carcinoma by targeting TFPI-2. Exp Ther Med 20:53 (2020). PubMed: 32952643
- Cao Y et al. Lysine-specific demethylase 2 contributes to the proliferation of small cell lung cancer by regulating the expression of TFPI-2. Mol Med Rep 18:733-740 (2018). PubMed: 29845195