製品の概要

  • 製品名Anti-TFEC antibody
    TFEC 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to TFEC
  • アプリケーション適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide:

    C-HITKQQTHPERN

    , corresponding to internal sequence amino acids 217-228 of Mouse TFEC.

  • ポジティブ・コントロール
    • Human Spleen and kidney tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/32000.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form.
  • 組織特異性Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon.
  • 配列類似性Belongs to the MiT/TFE family.
    Contains 1 basic helix-loop-helix (bHLH) domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bHLHe34 antibody
    • Class E basic helix-loop-helix protein 34 antibody
    • hTFEC-L antibody
    • TCFEC antibody
    • TFE-C antibody
    • Tfec antibody
    • TFEC protein antibody
    • TFEC_HUMAN antibody
    • TFECL antibody
    • Transcription factor EC antibody
    • Transcription factor EC-like antibody
    see all

Anti-TFEC antibody 画像

  • Human spleen (formalin-fixed, paraffin-embedded) stained with ab115569 at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Human kidney (formalin-fixed, paraffin-embedded) stained with ab115569 at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-TFEC antibody (ab115569) 使用論文

ab115569 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"