製品の概要

  • 製品名Anti-TFB1M antibody
    TFB1M 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to TFB1M
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length human TFB1M protein (AAH17788) with a tag.

  • ポジティブ・コントロール
    • TFB1M transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab77729 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 39 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.
  • 組織特異性Ubiquitously expressed.
  • 関連疾患Note=Variations in TFB1M may influence the clinical expression of aminoglycoside-induced deafness caused by the A1555G mutation in the mitochondrial 12S rRNA.
  • 配列類似性Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
  • 細胞内局在Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • N'-adenosyl(rRNA) dimethyltransferase 1 antibody
    • CGI75 antibody
    • Dimethyladenosine transferase 1, mitochondrial antibody
    • h-mtTFB antibody
    • h-mtTFB1 antibody
    • hmtTFB antibody
    • hmtTFB1 antibody
    • hTFB1M antibody
    • Mitochondrial 12S rRNA dimethylase 1 antibody
    • Mitochondrial dimethyladenosine transferase 1 antibody
    • Mitochondrial transcription factor B1 antibody
    • mtTFB1 antibody
    • S-adenosylmethionine-6-N' antibody
    • Tfb1m antibody
    • TFB1M_HUMAN antibody
    • Transcription factor B1 mitochondrial antibody
    see all

Anti-TFB1M antibody 画像

  • Anti-TFB1M antibody (ab77729) at 5 µg/ml + immunogen at 0.2 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

    Predicted band size : 39 kDa
    Observed band size : 64 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-TFB1M antibody (ab77729) at 5 µg/ml

    Lane 1 : TFB1M transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 39 kDa
    Observed band size : 39 kDa

Anti-TFB1M antibody (ab77729) 使用論文

ab77729 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab77729.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"