製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to TFB1M
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    C-ELKRRKSKNEEKE

    , corresponding to C terminal amino acids 325-337 of Human TFB1M (NP_057104.2)

  • ポジティブ・コントロール
    • A431 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106774 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 40 kDa).

ターゲット情報

  • 機能
    S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.
  • 組織特異性
    Ubiquitously expressed.
  • 関連疾患
    Note=Variations in TFB1M may influence the clinical expression of aminoglycoside-induced deafness caused by the A1555G mutation in the mitochondrial 12S rRNA.
  • 配列類似性
    Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
  • 細胞内局在
    Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • N'-adenosyl(rRNA) dimethyltransferase 1 antibody
    • CGI75 antibody
    • Dimethyladenosine transferase 1, mitochondrial antibody
    • h-mtTFB antibody
    • h-mtTFB1 antibody
    • hmtTFB antibody
    • hmtTFB1 antibody
    • hTFB1M antibody
    • Mitochondrial 12S rRNA dimethylase 1 antibody
    • Mitochondrial dimethyladenosine transferase 1 antibody
    • Mitochondrial transcription factor B1 antibody
    • mtTFB1 antibody
    • S-adenosylmethionine-6-N' antibody
    • Tfb1m antibody
    • TFB1M_HUMAN antibody
    • Transcription factor B1 mitochondrial antibody
    see all

Anti-TFB1M antibody 画像

  • Anti-TFB1M antibody (ab106774) at 0.3 µg/ml + A431 cell lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 40 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour

プロトコール

Anti-TFB1M antibody (ab106774) 使用論文

ab106774 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab106774.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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