The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 29 kDa (predicted molecular weight: 29 kDa).
TEX101 may play a role in signal transduction and promote protein tyrosine phosphorylation. It is detected in testis, spermatogonia and blood leukocytes but not detected in spermatocytes. Antibodies against TEX101 are present in sera from patients with scleroderma. There are two isoforms.
Korbakis D et al. Preclinical evaluation of a TEX101 protein ELISA test for the differential diagnosis of male infertility. BMC Med15:60 (2017).
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Korbakis D et al. Immunocapture-Selected Reaction Monitoring Screening Facilitates the Development of ELISA for the Measurement of Native TEX101 in Biological Fluids. Mol Cell Proteomics14:1517-26 (2015).
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