製品の概要

  • 製品名
    Tetrodotoxin citrate
  • 製品の詳細
    Na+ channel blocker; water-soluble
  • 別名
    • TTX
    • TTX citrate
  • 生理活性の詳細
    Water soluble citrate salt of tetrodotoxin. Potent, selective and reversible, use-dependent inhibitor of voltage-dependent Na+ channels.
  • 精製度
    > 98%
  • 特記事項
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法規制情報

製品の特性

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  • Cell-attached recording of a striatal cholinergic interneuron depicting TTX (100 nM) inhibition of spontaneous action potential firing. The open bar indicates time of TTX application.
  • Quantification of the p-S6rp signal in each striatal ChAt immunoreactive neuron after 1 hour incubation in control or TTX (1 M). Each dot corresponds to one neuron; each color corresponds to a different animal; dashed lines indicate the mean. Fluorescence values are normalized in arbitrary units (a.u.).

参考文献

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レビューと Q&A

The water-soluble TTX citrate ab120055 is not a citrate salt, it is simply TTX that has been dissolved in a citrate solution, and then lyophilized. So, it has the same molecular weight and formula as ab120054, which is soluble in pH 4.8 citrate buffer ...

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I contacted the laboratory regarding the difference between ab120054 and ab120055, and they responded that the only difference between these two compounds is that TTX citrate (ab120055) is the water soluble version, which accounts for the differen...

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Tetrodotoxin is very toxic and should be handled with caution. The safety datasheet is available from the datasheet.

Additionally, to neutralize the toxin, you may use a freshly made solution of 0.25% NaOCl + 0.25 N NaOH or a solution of 0.5%...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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