製品の概要

  • 製品名Anti-Tetanus Toxin antibody [TetE3]
    Tetanus Toxin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [TetE3] to Tetanus Toxin
  • アプリケーション適用あり: Neutralising, WB, ELISAmore details
  • 種交差性
    Reacts with Clostridium tetani.
  • 免疫原

    Supernatant from C. tetani.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab64755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Neutralising
WB
ELISA
  • 追加情報ELISA: Use at an assay dependent dilution.
    Neutralising activity, in vivo assay: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight (precursor): 151 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.
    • 細胞内局在Secreted
    • 別名
      • Tentoxylysin antibody
      • Tetanus toxin chain H antibody
      • Tetanus toxin chain L antibody
      • Tetanus toxin heavy chain antibody
      • Tetanus toxin light chain antibody
      see all

    Anti-Tetanus Toxin antibody [TetE3] (ab64755) 使用論文

    This product has been referenced in:
    • Kalb SR  et al. Extraction of BoNT/A, /B, /E, and /F with a single, high affinity monoclonal antibody for detection of botulinum neurotoxin by Endopep-MS. PLoS One 5: (2010). Read more (PubMed: 20808925) »

    See 1 Publication for this product

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    Thank you for contacting us.
    Yes, as soon as your Abreview is submitted the discount code can be used. Thus, you can go ahead now and use it on a future order before the expiration date.
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    Thank you for submitting an Abreview of ab64755. As you may have noticed, your review has now been published on our website.
    Since you obtained poor results using the antibody in an untested application, we would like to follow up on this to see i...

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    Application IHC - Wholemount
    Sample Mouse Tissue (Retina slice)
    Specification Retina slice
    Username

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    投稿 Jun 04 2012

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"